Oxaliplatin is a chemotherapy drug that contains platinum. Adjuvant treatment of colorectal cancer manufacturer. Other this section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Leucovorin calcium for injection rx only description leucovorin is one of several active, chemically reduced derivatives of folic acid. Insert a pdf file as an object into a powerpoint presentation. Oxaliplatin and laryngospasm introduction oxaliplatin eloxatin is a platinum compound with antineoplasmatic properties and is registered in the netherlands since 2005. In a fertility study, male rats were given oxaliplatin at 0, 0. Insertembed pdf file in powerpoint 2010 presentation. Eloxatin oxaliplatin for injection in combination with. Eloxatin oxaliplatin dose, indications, adverse effects.
Highlights of prescribing information reduce the dose of. You will receive this injection in a clinic or hospital setting. Known allergy to eloxatin or other platinum compounds. The good news is it only involves a few simple steps to do it. Ototoxicity is an unwanted effect of oxaliplatin in addition to sensory and motor neuropathy. Wear socks or gloves if you have to touch cold objects like cold flooring. I have a problem when i insert a pdf file in latex. How to crop pictures in word, excel, and powerpoint 2010. Convert an illustrator vector graphic to a powerpoint. To do this, you use one of the methods in the following examples. It may also be used to treat other types of cancers. Oxaliplatin injection usp may harm your unborn baby.
Colon cancer treatment regimens part 1 of 3 the selection, dosing, and administration of anticancer agents and the management of associated toxicities are complex. Highlights of prescribing information these highlights do not include all the information needed to use oxaliplatin injection, usp safely and effectively. Oxaliplatin is a diaminocyclohexane dachplatinum compound, active in several solid tumor types, including some cisplatincarboplatin refractory diseases, and licensed in the u. More and more of my presentations start to use video, and my preferred format for emailingdropboxing decks is pdf, so how do you insert a video in pdf. Start by opening both the excel worksheet and the powerpoint. Oxaliplatin oxaliplatin this product information is intended only for residents of the united states. Steps to convert ppt into elearning using adobe captivate 2017 syed amjad ali swift is an innovative elearning services company that provides endtoend elearning. When working in powerpoint, it is always important to package the presentation once you are done to ensure that the presentation is saved with all of its. Steps to convert ppt into elearning using adobe captivate. Link or embed a powerpoint slide in a word document. Largescale prospective pharmacogenomics study of oxaliplatin. Learn more about ispring suite authoring tool and get a free trial at this tutorial shows how to convert a powerpoint presentation to a scorm package. Dosage may be reduced, delayed or discontinued in patients with bone. Open your powerpoint presentation on the page you want to insert the pdf within.
How to convert powerpoint into an interactive elearning. Highlights of prescribing information adjuvant setting or. The administration of oxaliplatin injection does not require prehydration. Oxaliplatin is a new 3rdgeneration platinum analog.
Create and update powerpoint reports using r displayr. Preclinical studies have shown oxaliplatin to be synergistic with fluorouracil and sn38, the active metabolite of irinotecan. It is used in combination with other medications to slow or stop cancer cell growth. To insert a pdf file as an object into a powerpoint presentation, you make it available to those youre sharing the presentation. It is not known if oxaliplatin injection usp passes into your breast milk. Eloxatin is supplied in singleuse vials containing 50 mg or 100 mg of oxaliplatin. Medlineplus information on oxaliplatin a lay language summary of important information about this drug that may include the following. Manipulation of microsoft word and powerpoint documents. Appropriate management of therapy and complications is possible only when adequate diagnostic and treatment facilities are readily available. To keep a pdf file as a support document for your presentation insert the entire pdf into the presentation as an object that you can open and view during your presentation.
Office 365 subscription, office 2019, office 2016, office 20, office 2010. Link to the pdf file there and select the pdf file, then ok. Eloxatin is a platinumbased drug used in combination with infusional 5. It is believed to work via the formation of reactive platinum complexes, which inhibit dna synthesis by forming interstrand and intrastrand crosslinking of dna molecules, thus disrupting dna replication and transcription. I compare and contrast three tools for creating and updating powerpoint reports using r.
How to link or embed an excel worksheet in a powerpoint. Go to insert tab object double click package in the list of options then the create package. In terms of oxaliplatin, a drug that is nearly always given over 24 h, does the peak. Easy to read fda package insert, drug facts, dosage and administration, and adverse effects for adrucil fluorouracil. Insert pdf file content into a powerpoint presentation. Nov 10, 2019 numbness, tingling, or burning of the feet or hands or around the mouth or in the throat may happen with oxaliplatin. If you insert the slide into the document as a powerpoint object, word runs powerpoint when you doubleclick the slide, and you can use powerpoint. Efficacy after stopping oxaliplatin is similar to mfolfox6 plus panitumumab. Oxaliplatin is a thirdgeneration platinum derivative that possesses the additional mechanism of blocking dna replication and transcription. The efficacy of s1 plus oxaliplatin sox as postoperative adjuvant. Common side effects include numbness, feeling tired, nausea, diarrhea, and low blood cell counts. Dress warmly and cover the skin if you go out in the cold.
Several payment sources exist for cancer drugs in ontario, depending on the drug, disease indication, and how and where it is delivered. Tonicclonic seizure following cytoreductive surgery with. How to include existing pdf slides into my beamer presentation. To show content from a pdf on a slide take a picture of the part of a pdf that you want, and paste it on your slide. Docetaxel plus oxaliplatin with or without fluorouracil or. Oxaliplatin combined with irinotecan and 5fluorouracilleucovorin. Here are the steps to inserting a pdf file into a word document. Oxaliplatin is approved for the treatment of patients with advanced colorectal cancer when administered in combination with fluorouracil and leucovorin. Follow these steps to use adobe acrobat to combine or merge word, excel, powerpoint, audio, or video files, web pages, or existing pdfs. Save your presentation powerpoint or keynote as a pdf. Linking or embedding an excel worksheet into a powerpoint presentation is actually pretty straightforward, and the process for doing either is almost identical. Now, adobe document cloud esigning and pdf tools are built right into microsoft office 365. Find patient medical information for oxaliplatin intravenous on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Unfortunately, inserting pdf content is not possible when editing a presentation in powerpoint for the web.
You can either choose one of the files already uploaded on your site or upload a new pdf file. Oxaliplatin is also being studied in the treatment of other types of cancer. Any changes you make to these geogebra materials are saved in your powerpoint. Singleuse vials of 50 mg or 100 mg oxaliplatin as a sterile, preservativefree lyophilized powder for reconstitution. Oxaliplatin side effects, dosage, interactions drugs. Associations between glutathione stransferase pi ile105val and glyoxylate. Highlights of prescribing information these highlights do not include all the information needed to use eloxatin safely and effectively. Sometimes, there is a shape or vector graphic from a popular stock photo site that id like to edit and use in powerpoint. One of these unique features is inserting a pdf directly into excel. This page contains more warnings and precautions for oxaliplatin, including who should avoid this drug entirely.
Cannot insert object error when inserting pdf files. Eloxatin oxaliplatin dosing, indications, interactions. You insert an object or a file into a document, presentation, spreadsheet, or other microsoft office 2003 or microsoft office xp file. Combine or merge files into a single pdf, adobe acrobat dc. How to convert a powerpoint presentation to a scorm package.
For information on 5fluorouracil and leucovorin, see the respective package. Patients aged 18 years or older with highrisk stage ii and stage iii colorectal. Oxaliplatin injection prescribing information getwell oncology. Utilization of warm therapy may be more comfortable for patients with oxaliplatin associated sensory neuropathy. Please contact pfizer canada medical information at 1 800 4636001 with any comments or inquiries. Deleve, in druginduced liver disease third edition, 20. How to put video inside pdf powerpoint templates and.
Oxaliplatin, usp is an organoplatinum complex in which the platinum atom is complexed with 1,2diaminocyclohexanedach and with an oxalate ligand as a leaving group. Eloxatin oxaliplatin powder, for solution for intravenous use eloxatin oxaliplatin. The ceds recommendation was made on the basis that oxaliplatin. Gene signatures of drug resistance predict patient survival in. Highlights of prescribing information platinumresistant. If you encounter technical difficulties in viewing our product information please contact. Oxaliplatin is an organoplatinum structure in which the platinum atom is complexed with dach and with an oxalate ligand as leaving group figure 2. For information on 5fluorouracil and leucovorin, see the respective package inserts. Ask your pharmacist or doctor for a copy of the manufacturers information for the patient. Eloxatin oxaliplatin injection should be administered under the supervision of a quali. Excel provides a plethora of features for organizing, manipulating, and handling your data.
Often it is used together with fluorouracil and folinic acid leucovorin in advanced cancer. These highlights do not include all the information needed to use adynovate safely and effectively. Rearrange individual pages or entire files in the desired order. Sep 23, 2014 oxaliplatin showed no crossresistance with cisplatin and did not exhibit significant nephrotoxicity. Combine files into a single pdf, insert a pdf into another pdf, insert a clipboard selection into a pdf, or place insert a pdf as a link in another file. Cytoreductive surgery crs with hyperthermic intraperitoneal ip chemotherapy. The icon is blank when you insert an object or a file into. Finially i figured out a way to solve this pdf attachment problem on excel. How to link or embed an excel worksheet in microsoft powerpoint. Adding oxaliplatin to folfiri extends survival in metastatic colorectal cancer. To bring you great quality, smallpdf has partnered with solid documents that offers the best conversion out there.
Definition from the nci drug dictionary detailed scientific definition and other names for this drug. Chemotherapynaive patients with ras wildtype mcrc, aged. Adding weekly irinotecan to highdose 5fluorouracil and folinic acid. For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands. Oxaliplatin for adjuvant treatment of colorectal cancer. Oxaliplatin injection may increase the risk of genetic defects or fetal malformations and thus oxaliplatin injection is contraindicated in pregnancy, and males are advised not to father a child during treatment and up to 6 months thereafter. Oxaliplatin has been reported to exhibit cytotoxic.
How to embed word, excel, powerpoint and pdf in weebly. That means everyone in your organization can transact business and collaborate faster in their. The underlying assumption is that r is your computational engine and that you are trying to get outputs into powerpoint. Oxaliplatin, sold under the brand name eloxatin, is a cancer medication used to treat colorectal cancer. This is based on results in animals with other known arteriolar irritants. These symptoms will disappear in a few hours, and not require treatment. The ced recommended that oxaliplatin eloxatin be funded through cancer care ontarios new drug funding program for the adjuvant treatment of colorectal cancer according to specific criteria. See full prescribing information for oxaliplatin injection, usp. In a separate cohort, oxaliplatin 85 mgm 2 was administered on day 1 every 2 weeks, for a maximum of. Management of extravasation of oxaliplatin article pdf available in journal of oncology pharmacy practice 114. Nov 09, 2018 oxaliplatin is injected into a vein through an iv. This process will then insert a screenshot of your open pdf document window into the powerpoint presentation. Premedication with antiemetics, including 5ht3 blockers with or without dexamethasone, is recommended.
Treatment with oxaliplatin therapy may cause nausea, vomiting, diarrhea. See full prescribing information for complete boxed warning. Canadian regulations limit the scope of information we are permitted to give on prescription drugs via the internet or other means. Highlights of prescribing information thrombocytopenia. To keep a pdf file as a support document for your presentation insert the entire pdf into. As this emedtv resource discusses, people who have certain allergies or are pregnant should talk to their doctor before receiving oxaliplatin. Oxaliplatin combined with irinotecan and 5fluorouracilleucovorin ocfl in. Several genetic markers have been shown to predict oxaliplatininduced psn. If your pdf is in a presentation format, the conversion should be no problem.
For treating certain types of cancers such as colorectal, pancreatic and stomach cancer, usually in combination with other drugs such as 5fluorouracil. Also there is an option to open the file in new window when the user clicks on the link. Chronomodulation of lohp was shown to reduce neurotoxicity when compared to flat infusion of the same drug 17 but failed when compared with a classical 2. Interactive learning, teaching and evaluation resources created with geogebra can be shared and used by everyone at the geogebra app for powerpoint lets you insert interactive geogebra materials into your presentation. Docetaxel plus oxaliplatin with or without fluorouracil or capecitabine in metastatic or. Ways to convert powerpoint into an interactive elearning module. Eloxatin is supplied in singleuse vials containing 50 mg, 100 mg or 200 mg of oxaliplatin as a sterile, preservativefree, aqueous solution at a concentration of 5 mgml. Oxaliplatin administration is associated with sensory neuropathies that may be exacerbated or precipitated by cold temperatures or objects.
Oxaliplatin is used in combination with 5fluorouracil and folinic acid in the treatment of metastatic colorectal cancer. Oxaliplatin must be given slowly, and the infusion can take at least 2 hours to. Females who are able to become pregnant should avoid becoming pregnant and should use effective birth control during treatment with oxaliplatin injection usp. Eloxatin oxaliplatin powder, for solution for intravenous use eloxatin oxaliplatin concentrate, for solution for intravenous use initial u. The package insert states that there is no proven successful management of extravasation after it occurs, although sympathetic block and heparinization are commonly employed during acute management.
Prior drug therapy included treatment with an ace inhibitor ramipril. Oxaliplatin fda prescribing information, side effects and uses. Oxaliplatin is not generally crossresistant to cisplatin or carboplatin, possibly due to the dach group and resistance to dna mismatch repair. Please consult a qualified health professional for more detailed information.
Oxaliplatin, usp is slightly soluble in water at 6 mgml, very slightly soluble in methanol, and practically insoluble in ethanol and acetone. And editing the graphic in powerpoint, for me anyway, would be faster than editing the graphic in illustratorespecially considering the file is going to end up in powerpoint. Oxaliplatin injection eloxatin side effects, medical uses. Patients with metastatic or locally recurrent gastric adenocarcinoma. Eloxatin oxaliplatin injection for intravenous use. Oxaliplatininduced acute st segment elevation mimicking.
Oxaliplatin was clastogenic both in vitro chromosome aberration in human lymphocytes and in vivo mouse bone marrow micronucleus assay. From here, you can crop your screenshot, resize it, and position it. I am working on transfering my plots to a presentation using officer package in r. Knowledge and time are the 2 most valuable resources in the world that we currently live in and, now, we have many. In a second phase 1 study, oxaliplatin was administered to 26 pediatric patients as a 2hour intravenous infusion on day 1 every 3 weeks 1 cycle at 5 dose levels starting at 100 mgm 2 with escalation to 160 mgm 2, for a maximum of 6 cycles. S1 and oxaliplatin versus tegafururacil and leucovorin as. Drug dose modifications and schedule and initiation of supportive care interventions are often necessary because of expected toxicities and. Adding oxaliplatin to folfiri extends survival in metastatic. Persistence of highdose oxaliplatininduced neuropathy at long. Oxaliplatin 55,111 is used as neoadjuvant systemic treatment of colorectal metastases to the liver prior to surgical removal of the metastases, which is intended to convert unresectable cases into resectable ones. Oxaliplatin comes as a solution liquid to be injected into a vein. Eloxatin is supplied in singleuse vials containing 50 mg or 100 mg of oxaliplatin as a sterile, preservativefree lyophilized powder for reconstitution. Place your cursor by clicking on the area where you wish to insert the pdf document.
50 484 603 1216 716 278 1287 498 1357 1372 1169 1426 526 842 1509 723 45 238 545 1232 810 939 648 811 828 753 1592 174 169 1298 843 1583 333 167 143 1276 612 1212 686 1388 732 392 1414 1329 717 162 1279 629